ABSTRACT
OBJECTIVE: An antibiotic-sensitivity study was conducted on 117 strains of group A streptococcus (GAS), 60 strains of group G streptococcus (GGS) and 20 strains of group C streptococcus (GCS) in order to understand current resistance trends. METHODS: All strains were tested by the Kirby Bauer disc diffusion method to 15 antibiotics. Resistant strains were confirmed by testing the minimum inhibitory concentration (MIC) of antibiotics by broth dilution technique. RESULTS: Among GAS, highest resistance was observed to tetracycline (27.4%) and erythromycin (16.2%). The GGS and GCS tested, showed similar resistance patterns. CONCLUSION: All beta-hemolytic streptococci were susceptible to penicillin, amoxycillin, cephalosporins and linezolid. Resistance to erythromycin, tetracycline, clindamycin, chloramphenicol, and quinolones is emerging.
Subject(s)
Anti-Bacterial Agents/pharmacology , Child , Drug Resistance, Bacterial , Humans , Larynx/microbiology , Microbial Sensitivity Tests , Risk Factors , Sampling Studies , Sensitivity and Specificity , Streptococcus agalactiae/drug effects , Streptococcus pyogenes/drug effectsABSTRACT
BACKGROUND: The formation of granulation tissue is an important factor promoting recurrence after surgical treatment of laryngotracheal stenosis. Bacterial infection was claimed to be the cause. OBJECTIVE: The present study aimed to identify the bacteriology of granulation tissue in laryngotracheal stenosis patients. MATERIAL AND METHOD: Data was collected prospectively. Granulation tissue found in the site of laryngotracheal stenosis was removed and sent to the microbiologic study to identify the organisms. RESULTS: Twenty-four specimens from 17 patients were included in the present study. Coagulase-positive Staphylococcus (45.8%) was the most common gram-positive organism and Pseudomonas aeruginosa as well as Enterobacter species (16.7%) were the most common gram-negative bacteria. Ciprofloxacin may be the oral antibiotic that should be recommended. CONCLUSION: Coagulase-positive Staphylococcus, Pseudomonas aeruginosa as well as Enterobacter species were the common organisms identified from the granulation tissue in recurrent laryngotracheal stenosis. Oral antibiotics, such as ciprofloxacin, may have benefit in reducing the formation of this granulation tissue.
Subject(s)
Adolescent , Adult , Bacteria/isolation & purification , Child , Female , Granulation Tissue/microbiology , Humans , Laryngostenosis/microbiology , Larynx/microbiology , Male , Middle Aged , Trachea/microbiologyABSTRACT
A 58 year old male, chronic smoker, with diabetes mellitus (Type II), residing in Madhya Pradesh presented with dysphagia, hoarseness, odynophagia and significant weight loss. Microlaryngoscopy showed reddish ulcerated area involving valleculae, and pharyngo-epiglottic fold. Histopathological examination showed foamy macrophages containing Histoplasma capsulatum. Patient initially responded to Azoles, relapsed three months after stopping the treatment and presented with oral lesions. Biopsy showed H. capsulatum, histologically as well as on culture. The mycelial phase converted to yeast phase on B.H.I.A. at 37 degrees C confirming the isolate as H. capsulatum. The patient responded well to amphotericin B.
Subject(s)
Amphotericin B/therapeutic use , Antifungal Agents/therapeutic use , Disease Progression , Histoplasma/isolation & purification , Histoplasmosis/microbiology , Humans , Laryngeal Diseases/microbiology , Laryngoscopy , Larynx/microbiology , Male , Middle Aged , Mouth Diseases/microbiology , RecurrenceABSTRACT
Apresenta-se um caso de comprometimento criptococótico de laringe, em paciente com criptococose pulmonar. Näo foi encontrado, na literatura, descriçäo de comprometimento da mucosa laríngea, mesmo em casos de disseminaçäo da doença. O diagnóstico foi confirmado só pela necrópsia